(5-Chloro-2-Methoxy-4-pyridyl)boronic acid

(5-Chloro-2-Methoxy-4-pyridyl)boronic acid - Names and Identifiers

Name	(5-chloro-2-methoxy-4-pyridyl)boronic acid
Synonyms	oro-2-methoxypyridine-4-boronic acid 5-Chloro-2-methoxypyridine-4-boronicacid 5-Chloro-2-methoxypyridine-4-boronic acid (5-chloro-2-methoxy-4-pyridyl)boronic acid (5-Chloro-2-Methoxy-4-pyridyl)boronic acid 5-CHLORO-2-METHOXY-PYRIDINE-4-BORONIC ACID (5-Chloro-2-methoxypyridin-4-yl)boronicaci (5-Chloro-2-methoxypyridin-4-yl)boronic acid (5-CHLORO-2-METHOXYPYRIDIN-4-YL)BORONIC ACID (5-Chloro-2-methoxy-4-pyridinyl)boronic acid 5-CHLORO-2-METHOXYPYRIDIN-4-YL-4-BORONIC ACID Boronic acid, B-(5-chloro-2-methoxy-4-pyridinyl)- boronic acid, B-(5-chloro-2-methoxy-4-pyridinyl)- Boronic acid, (5-chloro-2-methoxy-4-pyridinyl)- (9CI)
CAS	475275-69-5
InChI	InChI=1/C6H7BClNO3/c1-12-6-2-4(7(10)11)5(8)3-9-6/h2-3,10-11H,1H3

(5-Chloro-2-Methoxy-4-pyridyl)boronic acid - Physico-chemical Properties

Molecular Formula	C6H7BClNO3
Molar Mass	187.39
Density	1.403g/cm³
Boling Point	347.608°C at 760 mmHg
Flash Point	164.028°C
Vapor Presure	0mmHg at 25°C
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.546

(5-Chloro-2-Methoxy-4-pyridyl)boronic acid - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

(5-Chloro-2-Methoxy-4-pyridyl)boronic acid - Introduction

boronic acid, the chemical formula is C7H8BClNO3, is an organic boron compound. It has the following properties:

1. Appearance:(5-chloro-2-methoxy-4-pyridyl)boronic acid is a white crystalline solid.

2. solubility: soluble in most organic solvents, insoluble in water.

3. chemical reaction:(5-chloro-2-methoxy-4-pyridyl)boronic acid can participate in the synthesis reaction of benzene borate and be used as a chemical reagent for the construction of C- C bonds.

4. use:(5-chloro-2-methoxy-4-pyridyl)boronic acid is an important organic synthesis intermediates, commonly used in medicine and pesticide research and development. It can be used to prepare various compounds, such as drugs, pesticides and photoelectric functional materials.

Preparation Method:
boronic acid can be synthesized by oxidation-boronation reaction. The specific method is that 2-methoxy-5-chloropyridine reacts with triethyl boron in triethylamine under an oxygen atmosphere to obtain the target product.

Safety Information:
boronic acid has low toxicity under general use conditions. However, it is still necessary to follow general laboratory safety procedures during operation, such as wearing appropriate personal protective equipment (such as gloves, glasses, etc.) to avoid inhalation or contact with skin. Care should be taken to avoid contact with strong oxidants and other hazardous chemicals during handling and storage. In addition, since boronic acid is an organic compound, it should be handled in a well-ventilated environment to avoid contact with high temperature or open flame. In the event of an accident or eating, medical help should be sought immediately.

Last Update：2024-04-09 21:04:16